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Updated: Apr 6, 2026

08:37
Development of a Quantitative Recombinase Polymerase Amplification Assay with an Internal Positive Control
Published on: March 30, 2015
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Red light-controlled polymerase chain reaction
A Meyer1, Margot Schikora, A Mokhir
1Friedrich-Alexander-University of Erlangen-Nürnberg, Department of Chemistry and Pharmacy, Organic Chemistry Chair II, Henkestr. 42., 91054 Erlangen, Germany. Andriy.Mokhir@fau.de.
Abstract:
A 23-mer DNA "caged" at its 3'-terminus with a 9-anthracenyl moiety was prepared. It can be uncaged in the presence of photosensitizer (In(pyropheophorbide-a)chloride)-containing DNAs (9-12 mers) and upon irradiation with red light. This mixture of DNAs was used to design red-light controlled polymerase chain reaction.
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