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Updated: Apr 6, 2026

Real-Time Electrocardiogram Monitoring During Treadmill Training in Mice
Published on: May 5, 2022
Monitoring athletic training status using the maximal rate of heart rate increase
Clint R Bellenger1, Rebecca L Thomson1, Peter R C Howe2
1Alliance for Research in Exercise, Nutrition and Activity (ARENA), Sansom Institute for Health Research, University of South Australia, Australia.
Objectives:
Reductions in maximal rate of heart rate increase (rHRI) correlate with performance reductions when training load is increased. This study evaluated whether rHRI tracked performance changes across a range of training states.
Design:
Prospective intervention.
Methods:
rHRI was assessed during five min of cycling at 100W (rHRIcyc) and running at 8km/h (rHRIrun) in 13 male triathletes following two weeks of light-training (LT), two weeks of heavy-training (HT) and a two-day recovery period (RP). A five min cycling time-trial assessed performance and peak oxygen consumption (V˙O2peak).
Results:
Performance likely decreased following HT (Effect size±90% confidence interval=-0.18±0.09), then very likely increased following RP (0.32±0.14). rHRIcyc very likely decreased (-0.48±0.24), and rHRIrun possibly decreased (-0.33±0.48), following HT. Changes in both measures were unclear following RP. Steady-state HR was almost certainly lower (-0.81±0.31) during rHRIcyc than rHRIrun. A large correlation was found between reductions in performance and rHRIrun (r±90%; CI=0.65±0.34) from LT to HT, but was unclear for rHRIcyc. Trivial within-subject correlations were found between rHRI and performance, but the strength of relationship between rHRIrun and performance was largely associated with V˙O2peak following LT (r=-0.58±0.38).
Conclusions:
Performance reductions were most sensitively tracked by rHRIrun following HT. This may be due to rHRIrun being assessed at a higher intensity than rHRIcyc, inferred from a higher steady-state HR and supported by a stronger within-subject relationship between rHRIrun and performance in individuals with a lower V˙O2peak, in whom the same exercise intensity would represent a greater physiological stress. rHRI assessed at relatively high exercise intensities may better track performance changes.
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