Related Experiment Video
Updated: Aug 19, 2026

Establishment of Acute Pontine Infarction in Rats by Electrical Stimulation
Published on: August 27, 2020
Urinary incontinence a first presentation of central pontine myelinolysis: a case report
Asmah Hassan Syed1, Joanna Shak2, Ali Alsawaf2
1Ipswich Hospital NHS Trust, Ipswich, UK.
Abstract:
An 84-year-old lady was treated for hyperosmolar hyperglycaemia with IV insulin, fluids and catheterisation for fluid balance monitoring. Trial without catheter failed as the patient complained of new-onset urinary incontinence and lack of awareness of bladder filling. In light of her breast cancer history, we excluded cauda equina. Ultrasound KUB showed an enlarged bladder. Whole-body MRI revealed a lesion in the pons which was highly suggestive of central pontine myelinolysis (CPM). Her electrolytes were normal throughout her admission; thus, the rapid fluctuation in osmolality, secondary to her hyperglycaemic state, was the likely cause of CPM. CPM has been reported secondary to hyperglycaemia; however, this is the first reported case of CPM presenting as urinary incontinence and loss of bladder sensation.
More Related Videos
Related Concept Videos
Neural Regulation
The Micturition Reflex
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating urine...
Multiple Sclerosis l: Introduction
Alterations in Muscle Tone lll

