Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies for Cardiovascular System II:Types of Echocardiography01:20

Imaging Studies for Cardiovascular System II:Types of Echocardiography

869
Echocardiography plays a role in assessing cardiac health and detecting heart conditions, with various types providing critical insights for diagnosis and treatment.
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for...
869
Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

9.1K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
9.1K
Imaging Studies for Cardiovascular System I:Echocardiography01:17

Imaging Studies for Cardiovascular System I:Echocardiography

930
Cardiac imaging studies encompass a wide range of noninvasive and minimally invasive techniques designed to visualize the heart's structure and function in detail. One such technique is echocardiography, which uses high-frequency ultrasound waves to produce detailed images of the heart, known as echocardiograms.
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
930
Dysrhythmias V: Evaluating Dysrhythmias01:30

Dysrhythmias V: Evaluating Dysrhythmias

478
Dysrhythmias, also known as arrhythmias, are disturbances in the heart's rhythm that range from benign to life-threatening. A thorough evaluation is crucial for appropriate management and involves a comprehensive medical history, physical examination, and various diagnostic tests.Medical HistorySymptoms: Collect detailed information on palpitations, dizziness, syncope, chest pain, and fatigue. Note their onset, frequency, and triggers.Previous Cardiac Issues: Document any history of heart...
478
The Thyroid Gland01:23

The Thyroid Gland

8.8K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
8.8K
Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

6.7K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
6.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Burden of Congenital Hypothyroidism Without Newborn Screening: Clinical and Cognitive Findings from a Multicenter Study in Algeria.

International journal of neonatal screening·2025
Same author

Delayed Thyrotropin Rise in Preterm Newborns: Value of Multiple Screening Samples and of a Detailed Clinical Characterization.

Thyroid : official journal of the American Thyroid Association·2025
Same author

Rarity of Congenital Adrenal Hyperplasia in Children Born Very Preterm: Possible Mechanism and Implication for Newborn Screening.

Hormone research in paediatrics·2025
Same author

Revue medicale suisse·2024
Same author

Hypothyroidism due to biallelic variants in IYD: description of 4 families and a novel variant.

European journal of endocrinology·2024
Same author

Severe Aldosterone Synthase Deficiency in a 9-Day-Old Lebanese Boy: The Importance of Functional Studies to Establish Pathogenicity of Seemingly Benign Variants in CYP11B2.

Hormone research in paediatrics·2024

Related Experiment Video

Updated: Apr 6, 2026

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
05:41

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis

Published on: February 9, 2024

1.2K

Interpreting Minor Variations in Thyroid Function or Echostructure: Treating Patients, Not Numbers or Images.

Guy Van Vliet1, Johnny Deladoëy2

  • 1Department of Pediatrics, Endocrinology Service and Research Center, Centre Hospitalier Universitaire Sainte-Justine, 3175 chemin de la Côte-Ste-Catherine, Montréal, Quebec H3T 1C5, Canada.

Pediatric Clinics of North America
|July 27, 2015
PubMed
Summary

Thyroid function tests and neck ultrasounds are frequently overused for nonspecific symptoms. Repeat testing and careful interpretation are crucial to avoid unnecessary treatment and patient anxiety regarding thyroid nodules.

Keywords:
ChildrenHyperthyroidismHypothyroidismIncidentalNoduleOvertThyroidUltrasonography

More Related Videos

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
03:55

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

1.1K
A Personalized 3D-Printed Model for Preoperative Evaluation in Thyroid Surgery
04:42

A Personalized 3D-Printed Model for Preoperative Evaluation in Thyroid Surgery

Published on: February 17, 2023

2.0K

Related Experiment Videos

Last Updated: Apr 6, 2026

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
05:41

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis

Published on: February 9, 2024

1.2K
Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
03:55

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

1.1K
A Personalized 3D-Printed Model for Preoperative Evaluation in Thyroid Surgery
04:42

A Personalized 3D-Printed Model for Preoperative Evaluation in Thyroid Surgery

Published on: February 17, 2023

2.0K

Area of Science:

  • Endocrinology
  • Diagnostic Imaging
  • Laboratory Medicine

Background:

  • Thyroid function tests (serum thyrotropin and T4) are often ordered for nonspecific complaints, leading to potential misinterpretation.
  • Laboratory reference ranges, particularly adult ranges, may not be appropriate for pediatric populations, increasing the risk of false positives.
  • Neck ultrasounds are commonly performed for various thyroid conditions, including diffuse goiter, and incidental findings can cause undue concern.

Purpose of the Study:

  • To evaluate the appropriate use of thyroid function tests and neck ultrasounds in clinical practice.
  • To highlight the limitations of standard laboratory reference ranges and the implications of incidental ultrasound findings.
  • To emphasize the need for judicious testing and interpretation in diagnosing thyroid conditions like Hashimoto thyroiditis.

Main Methods:

  • Review of current practices in ordering thyroid function tests.
  • Analysis of the utility and interpretation of neck ultrasound findings.
  • Discussion of diagnostic criteria for common thyroid disorders.

Main Results:

  • Thyroid function tests frequently fall outside reference ranges due to statistical variation (5% of the time) and inappropriate range application.
  • Regression toward the mean necessitates repeat testing before initiating treatment for suspected thyroid dysfunction.
  • Incidental small cysts and nodules on neck ultrasounds often lead to unnecessary investigations for neoplasia, despite not being required for diagnosing Hashimoto thyroiditis.

Conclusions:

  • Overt thyroid dysfunction is overdiagnosed due to inappropriate test ordering and interpretation.
  • Neck ultrasounds should be used judiciously, as incidental findings can lead to patient anxiety and unnecessary procedures.
  • Accurate diagnosis of thyroid conditions relies on appropriate clinical context, repeat testing, and understanding test limitations.