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Author Spotlight: A Model to Study the Systemic and Local Dynamics of CD8+ T Cells During LN Metastasis
Published on: January 26, 2024
Potential Use of Transferred Lymph Nodes as Metastasis Detectors after Tumor Excision
Fabio Nicoli1, Pedro Ciudad2, Seong Yoon Lim2
1Department of Plastic and Reconstructive Surgery, China Medical University Hospital, Taichung, Taiwan. ; Department of Plastic and Reconstructive Surgery, University of Rome Tor Vergata, Roma, Italy. ; Plastic, Reconstructive, and Aesthetic Surgery, Villa Salaria Clinic, Rome, Italy.
Abstract:
Due to the fact that it reliably results in positive outcomes, lymph node flap transfer is becoming an increasingly popular surgical procedure for the prevention and treatment of lymphedema. This technique has been shown to stimulate lymphoangiogenesis and restore lymphatic function, as well as decreasing infection rates, minimizing pain, and preventing the recurrence of lymphedema. In this article, we investigate possible additional benefits of lymph node flap transfer, primarily the possibility that sentinel lymph nodes may be used to detect micro-metastasis or in-transit metastasis and may function as an additional lymphatic station after the excision of advanced skin cancer.

