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A 2-D guinea pig lung proteome map.

Simone Schuller1, Kjell Sergeant2, Jenny Renaut2

  • 1University College Dublin, School of Veterinary Medicine, Belfield, Dublin 4, Ireland ; Vetsuisse Faculty University of Bern, Länggassstrasse 128, 3012 Bern, Switzerland.

Data in Brief
|July 29, 2015
PubMed
Summary
This summary is machine-generated.

Researchers created a 2-D guinea pig proteome map with 486 protein identifications and post-translational modifications (PTMs). This resource aids in annotating the guinea pig genome and advancing pulmonary research using advanced techniques.

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Area of Science:

  • Proteomics
  • Genomics
  • Animal Models

Background:

  • Guinea pigs are a key model for studying pulmonary diseases.
  • Recent sequencing of the guinea pig genome enables advanced 'omics' research.

Purpose of the Study:

  • To create a 2-D guinea pig proteome map for genome annotation.
  • To support future pulmonary proteomics research in guinea pigs.

Main Methods:

  • Construction of a 2-D guinea pig proteome map.
  • Identification of 486 proteins and their post-translational modifications (PTMs).

Main Results:

  • A comprehensive 2-D guinea pig proteome map was generated.
  • The map includes 486 identified proteins and various PTMs.
  • Data is accessible via the UCD 2D-PAGE database and PeptideAtlas.

Conclusions:

  • The guinea pig proteome map is a valuable resource for genomic and proteomic research.
  • Facilitates deeper understanding of pulmonary diseases in this model organism.