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Experimental Study of the Pathogenicity of Pasteurella multocida Capsular Type B in Rabbits
S Katoch1, L Verma1, M Sharma1
1Department of Veterinary Microbiology, Dr. G. C. Negi College of Veterinary and Animal Sciences, Palampur, Himachal Pradesh, India.
Pasteurella multocida capsular type B causes severe respiratory disease and death in rabbits. This finding is crucial for understanding rabbit pasteurellosis and implementing control measures.
Area of Science:
- Veterinary Microbiology
- Animal Pathology
Background:
- Pasteurella multocida is a significant bacterial pathogen in rabbits.
- Capsular types A and D are known to cause disease, but the pathogenicity of type B was less understood.
Purpose of the Study:
- To investigate the pathogenicity of Pasteurella multocida capsular type B in rabbits.
- To determine the clinical and pathological effects of type B infection.
Main Methods:
- Ten rabbits were divided into two groups.
- Group I was intranasally inoculated with Pasteurella multocida type B (2 × 10^5 CFU/ml).
- Group II received a phosphate-buffered saline control.
Main Results:
- Infected rabbits (Group I) exhibited respiratory distress, fever, and severe dyspnea.
- Mortality occurred within 24-48 hours post-infection.
- Pathological findings included tracheal congestion/hemorrhage, pneumonia, bacteremia, and septicemia.
Conclusions:
- Pasteurella multocida capsular type B is highly pathogenic in rabbits.
- This capsular type can cause severe respiratory disease and septicemia, similar to types A and D.
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