Septins are protein filaments forming the cytoskeleton along with the microtubules, microfilaments, intermediate filaments, and other accessory proteins. In 1971 while studying the cell division cycle in mutant Saccharomyces cerevisiae Harwell et al. first identified the septin-related genes playing a crucial role in yeast cytokinesis. Fluorescence microscopy revealed that these proteins localize at the budding neck as rings. These ring-like proteins were then named Septins by John Pringle, and...

The Aggregate Cement ratio refers to the weight of aggregate divided by the weight of cement in a concrete mix. Altering this ratio has profound effects on the concrete's properties. This ratio plays a pivotal role in determining the strength, workability, and durability of concrete. When the Aggregate Cement ratio is higher, the mix is leaner, meaning it has less cement paste to lubricate the aggregate, potentially making the concrete less workable. Such mixes, known as lean, enhance the...

Portland cement is the essential binding ingredient in concrete, made from finely ground materials including lime, iron, silica, and alumina. Lime is derived primarily from limestone, marble, marl, seashells, and clays, which also supply iron and alumina, while silica is sourced from sand, chalk, and bauxite. Contemporary manufacturing of Portland cement is a significant source of carbon dioxide emissions, prompting research into reducing its content in concrete through alternative...

Deleterious substances in aggregates can be detrimental to the quality and durability of concrete. These substances include organic impurities like loam, which interfere with cement hydration and are usually present in the sand. These prevent a good bond between aggregate and cement paste. Organic impurities can be detected using the colorimetric test, where the darkness of a solution after agitation indicates the level of organic content.
Another type of impurity is clay and fine material that...

Concreting at elevated temperatures accelerates the hydration process, leading to quicker setting but potentially reducing the long-term strength of the concrete structure. Additionally, low air humidity fosters rapid moisture loss from the concrete, resulting in reduced workability, pronounced plastic shrinkage, and a higher likelihood of crazing.
Mitigating the heat increase in concrete can be economically achieved by shading aggregate stockpiles to prevent heating from solar radiation,...

Segregation in fresh concrete is a phenomenon where the components of the concrete mix separate, leading to uneven distribution and compromised structural integrity. This separation typically occurs when concrete is subjected to excessive horizontal movement within forms, or when it is dropped from considerable heights or forced through narrow, winding paths. As a result, heavier coarse aggregate particles settle at the bottom, while lighter, finer materials such as cement and water rise to the...