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Related Concept Videos

Alterations in Blood Pressure01:30

Alterations in Blood Pressure

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Alterations in blood pressure, such as hypertension (high blood pressure) and hypotension (low blood pressure), significantly affect human health. Understanding these conditions' classifications, causes, and symptoms is essential for effective management and treatment.
Hypertension (High blood pressure)
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The movement of blood in a human body, commonly referred to as blood flow, is determined by the volume of blood that traverses a certain section of the bodily system per unit time. It is the rhythmic contraction of the heart's ventricles that primarily instigates this movement. As the ventricles contract, blood is forced into the prominent arteries, which then flow from areas of greater pressure to lower pressure areas. This movement continues into smaller arteries and arterioles and...
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Blood pressure (BP) is the pressure or force of blood exerted on the artery's walls as it circulates through the body. It is essential for maintaining blood flow throughout the body.
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Through-the-Wall Blood Sampling Method to Minimize Sleep Disruption in Clinical Settings
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Night time blood pressure dip.

Dennis Bloomfield1, Alex Park1

  • 1Dennis Bloomfield, Alex Park, Department of Medicine, Richmond University Medical Center, Staten Island, NY 10310, United States.

World Journal of Cardiology
|July 31, 2015
PubMed
Summary

Ambulatory blood pressure monitoring reveals normal blood pressure dips during sleep are 10-20%. This study questions if blunted nocturnal blood pressure dips or white coat hypertension truly predict cardiovascular events.

Keywords:
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Area of Science:

  • Cardiology
  • Hypertension Research
  • Sleep Medicine

Background:

  • Ambulatory blood pressure monitoring (ABPM) allows assessment of blood pressure during sleep.
  • The normal circadian fall in blood pressure during sleep is termed the 'dip', typically 10-20%.
  • Blunted or absent nocturnal dips (<10%) have been associated with adverse cardiovascular events.

Purpose of the Study:

  • To critically evaluate the predictive value of nocturnal blood pressure dipping for cardiovascular events.
  • To question the established significance of white coat hypertension as a precursor to essential hypertension.
  • To explore alternative factors influencing cardiovascular risk beyond traditional dip measures.

Main Methods:

  • Review and critical analysis of existing literature on ABPM and hypertension.
  • Discussion of the definition and measurement variability of the nocturnal blood pressure dip.
  • Comparative analysis of cardiovascular risk in medicated versus non-medicated white coat hypertensive patients.

Main Results:

  • The predictive value of blunted nocturnal dips for cardiovascular events is questioned.
  • The role of white coat hypertension as a predictor of essential hypertension is debated.
  • The importance of actual nighttime systolic blood pressure over dip measures is highlighted.

Conclusions:

  • Further research is needed to determine the clinical significance of nocturnal blood pressure dipping.
  • The relationship between white coat hypertension and essential hypertension requires re-evaluation.
  • The potential impact of sleep quality and duration on cardiovascular risk warrants investigation.