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The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
Published on: June 30, 2014
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Stable neuropsychiatric status in multiple sclerosis: a 3-year study.
Shumita Roy1, Jonathan Rodgers1, Allison S Drake1
1Department of Neurology, University at Buffalo, USA.
Multiple Sclerosis (Houndmills, Basingstoke, England)
|August 1, 2015
Summary
Multiple sclerosis (MS) patients did not show significant personality or neuropsychiatric changes over three years compared to healthy individuals. Motor and cognitive functions remained impaired, with only ambulation slowing over time.
Area of Science:
- Neuroscience
- Clinical Psychology
- Neurology
Background:
- Multiple sclerosis (MS) is associated with personality changes and neuropsychiatric symptoms.
- Previous research has not longitudinally assessed these changes in MS patients compared to healthy controls.
Purpose of the Study:
- To evaluate changes in personality traits and neuropsychiatric symptoms in multiple sclerosis patients over a 3-year period.
- To compare these changes against a healthy control group.
- To assess associated changes in motor and cognitive functions.
Main Methods:
- Longitudinal study over 3 years.
- Utilized NEO Five Factor Inventory for personality traits.
- Employed the Neuropsychiatric Inventory for neuropsychiatric symptoms.
- Assessed ambulation, manual dexterity, and cognitive function.
Main Results:
- No significant changes in personality traits or neuropsychiatric status were observed in MS patients relative to controls.
- MS patients exhibited persistent impairments in motor and cognitive functions at baseline and follow-up.
- A notable finding was the slowing of ambulation over the 3-year study period.
Conclusions:
- Neuropsychiatric status in multiple sclerosis patients remains stable over a 3-year timeframe.
- Despite stable neuropsychiatric symptoms, motor and cognitive deficits persist, with ambulation decline being a key indicator.
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