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Garré's sclerosing osteomyelitis: case report
Frederico Barra de Moraes1, Tainá Melo Vieira Motta1, Alessandra Assis Severin1
1Department of Orthopedics and Traumatology, School of Medicine, Universidade Federal de Goiás, Goiânia, GO, Brazil.
Revista Brasileira De Ortopedia
|August 1, 2015
Summary
This case report details a rare instance of Garré's sclerosing osteomyelitis in a patient with a history of lupus and osteoporosis. The study highlights diagnostic challenges and emphasizes the importance of considering chronic, low-virulence infections.
Area of Science:
- Orthopedics
- Infectious Diseases
- Radiology
Background:
- Garré's sclerosing osteomyelitis is a rare, chronic form of osteomyelitis.
- The patient had a history of long-term corticosteroid and alendronate use, potentially influencing her condition.
- The case presented with subtle symptoms, including edema and limited knee movement, without fever.
Observation:
- A 54-year-old woman presented with chronic left knee pain, edema, and limited mobility.
- Radiographic and MRI findings revealed signs of low-virulence, slow-progressing osteomyelitis in the femur and tibia.
- Biopsy confirmed chronic infection and inflammation, but cultures were negative.
Findings:
- Despite negative cultures, a diagnosis of Garré's sclerosing osteomyelitis was made.
- The etiology remained unclear, with suspected low-virulence bacterial infection.
- Differential diagnoses included fibrous dysplasia, SAPHO syndrome, and various bone tumors.
Implications:
- Highlights the diagnostic challenges of rare osteomyelitis forms, especially with negative cultures.
- Emphasizes the importance of considering chronic inflammatory and infectious processes in patients with long-term medication use.
- Underscores the need for comprehensive differential diagnosis in complex bone pathologies.