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The In ovo CAM-assay as a Xenograft Model for Sarcoma

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Calcaneal chondrosarcoma: a case report.

Frederico Barra de Moraes¹, Nicolle Diniz Linhares¹, Pryscilla Moreira de Souza Domingues¹

¹Faculdade de Medicina da Universidade Federal de Goiás, Goiânia, GO, Brazil.

Revista Brasileira De Ortopedia

|August 1, 2015

Summary

This case report details a rare chondrosarcoma of the calcaneus in a young adult. Early diagnosis and investigation are crucial for managing this aggressive bone cancer.

Keywords:

Bone neoplasms Calcaneus Chondrosarcoma

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Area of Science:

Orthopedic Oncology
Skeletal Radiology

Background:

Chondrosarcoma is a rare malignant bone tumor.
Calcaneal chondrosarcomas are exceptionally uncommon, particularly in young adults.

Observation:

A 30-year-old woman presented with a painless calcaneal nodule of 8 years duration, which became painful.
Imaging revealed an aggressive, osteolytic lesion involving the calcaneus, talus, and lateral malleolus with soft tissue invasion.

Findings:

Histological diagnosis confirmed chondrosarcoma.
The patient underwent multiple amputations due to local recurrence.
Metastasis to soft tissues and lungs occurred, leading to death 22 months post-diagnosis.

Implications:

This case highlights the rarity and aggressive nature of calcaneal chondrosarcoma in young individuals.
Emphasizes the importance of early diagnostic investigation, including advanced imaging, for prompt management.
Timely intervention may improve outcomes and reduce the risk of malignant transformation and mortality.