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Hospitalizations and deaths due to pertussis in children from 1996 to 2013
Janayne F Mançaneira1, Juliana R Benedetti1, Linjie Zhang1
1Medical School, Universidade Federal do Rio Grande (FURG), Rio Grande, RS, Brazil.
Insights
Pertussis (whooping cough) hospitalizations and deaths significantly increased in Brazilian children from 2011-2013. Infants under one year old were the most affected group, highlighting a critical public health concern.
Area of Science:
- Pediatrics
- Infectious Diseases
- Public Health Epidemiology
Background:
- Pertussis, also known as whooping cough, is a highly contagious respiratory infection.
- Vaccination has historically reduced pertussis incidence, but outbreaks can still occur.
- Understanding temporal trends in pertussis is crucial for public health interventions.
Purpose of the Study:
- To analyze the trends in pertussis-related hospitalizations and deaths among Brazilian children between 1996 and 2013.
- To identify specific age groups and geographical regions most impacted by pertussis during the study period.
Main Methods:
- A descriptive ecological study design was employed.
- Data on pertussis hospitalizations and deaths in children up to 19 years of age were obtained from the DATASUS database (1996-2013).
- Descriptive statistical analyses were used to assess temporal trends.
Main Results:
- A total of 19,047 pertussis hospitalizations and 498 deaths were recorded during the study period.
- Infants under one year old accounted for 88.2% of hospitalizations and 96.8% of deaths.
- A notable increase in hospitalizations and deaths occurred in the years 2011, 2012, and 2013 across all Brazilian regions, particularly in the Southeast, North, and Northeast.
Conclusions:
- A significant surge in pertussis hospitalizations and deaths was observed in Brazilian children during 2011-2013.
- Infants under one year represent the most vulnerable population to severe pertussis outcomes.
- These findings underscore the need for enhanced pertussis surveillance and vaccination strategies in Brazil.
Objectives:
To assess temporal trends of hospitalizations and deaths from pertussis in Brazilian children in the period of 1996-2013.
Methods:
This was a descriptive ecological study of temporal trends, based on the DATASUS database. The number of hospitalizations and deaths from pertussis in children up to 19 years of age from January 1996 to December 2013 was obtained. Descriptive statistics were applied for data analysis.
Results:
During the study period, a total of 19,047 hospital admissions from pertussis were recorded, of which 88.2% occurred in infants younger than 1 year. In the period 1996-2010, the mean annual number of admissions was 755, ranging from a maximum of 1179 in 2004 to a minimum of 400 in 2010. There was an increase of admissions in the last three consecutive years (2011, 2012, and 2013) with 1177, 2954 and 3589 hospitalizations, respectively. There were 498 deaths from pertussis throughout the study period, of which 96.8% occurred in children younger than one year. There was an increase in the number of deaths from pertussis in children in the years 2011, 2012, and 2013, with 40, 93, and 87 recorded deaths, respectively. The increase in hospitalizations and deaths from pertussis in children occurred in all regions of the country, with the highest increase observed in the Southeast, North and Northeast regions.
Conclusions:
There was a substantial increase in hospitalizations and deaths from pertussis in children for three consecutive years (2011, 2012, and 2013) in all Brazilian regions. The most affected age group was that of children younger than one year.
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