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Related Concept Videos

Depressive Disorders: Etiology01:27

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Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
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Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
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Related Experiment Video

Updated: Apr 6, 2026

A New Method for Inducing a Depression-Like Behavior in Rats
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Depression and violence: a Swedish population study.

Seena Fazel, Achim Wolf, Zheng Chang

    The Lancet. Psychiatry
    |August 4, 2015
    PubMed
    Summary

    Individuals with depression face a significantly increased risk of violent crime, even after accounting for genetic and social factors. This highlights the need for violence risk assessments in clinical depression care.

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    Area of Science:

    • Psychiatry
    • Criminology
    • Epidemiology

    Background:

    • Depression is linked to adverse outcomes like suicide and mortality.
    • The association between depression and violent crime requires further investigation.

    Purpose of the Study:

    • To determine the risk of violent crime in patients diagnosed with depression.
    • To examine the link between depressive symptoms and violent crime in a twin cohort.

    Main Methods:

    • Two Swedish studies were conducted: a total population study and a twin study.
    • The population study analyzed diagnoses of depressive disorders (n=47,158) against matched controls (n=898,454).
    • Sibling comparisons and twin data assessed familial and individual factors influencing the depression-violence association.

    Main Results:

    • Individuals with depression showed a 3-fold increased odds of violent crime compared to controls.
    • Increased violent crime risk was observed in siblings of depressed patients, indicating familial influence.
    • The association persisted after controlling for substance abuse, sociodemographics, and prior criminality, and in twin analyses.

    Conclusions:

    • Depression is independently associated with an increased risk of violent crime.
    • Clinical guidelines should incorporate violence risk assessments for specific patient subgroups with depression.