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Updated: Apr 6, 2026

Generating Recombinant Avian Herpesvirus Vectors with CRISPR/Cas9 Gene Editing
Published on: January 7, 2019
Identification of recombination between Muscovy duck parvovirus and goose parvovirus structural protein genes
Hongxing Shen1, Wen Zhang2, Hua Wang2
1Medical College, Jiangsu University, 301 Xuefu Road, Zhenjiang, 212013, People's Republic of China. hxshen@ujs.edu.cn.
Abstract:
Waterfowl parvoviruses are divided into Muscovy duck parvoviruses (MDPVs) and goose parvoviruses (GPVs). Phylogenetic analysis based on structural gene nucleotide sequences showed that the strains of three GPVs (DY, PT and D strains) and two MDPVs (GX5 and SAAH-SHNH) are closely related and formed one cluster. Recombination analysis showed that recombination between GPV-GDFsh and MDPV-89384/FRANCE strains led to five recombinant strains: GPV-DY, GPV-PT, GPV-D, MDPV-GX5 and MDPV-SAAH-SHNH. The recombinant event was confirmed using the Simplot program and phylogenetic analysis. This is the first comprehensive investigation of recombination between MDPV and GPV structural genes.
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