Related Experiment Video
Updated: Aug 4, 2026

Non-restraining EEG Radiotelemetry: Epidural and Deep Intracerebral Stereotaxic EEG Electrode Placement
Published on: June 25, 2016
[Seizures and respiratory failure following local anaesthesia administered for circumcision]
Ida Louise Heiberg1, Lars Nebrich, Pernille Pedersen
1Børneafdelingen, Hvidovre Hospital, Kettegård Allé 30, 2650 Hvidovre. ida.louise.heiberg@regionh.dk.
Insights
Local anesthesia for ritual circumcision can cause seizures and breathing problems in infants. Careful dosing and preparedness for complications are crucial for pediatric surgical safety.
Area of Science:
- Pediatric Anesthesiology
- Pediatric Surgery
- Neonatal Medicine
Background:
- Ritual circumcision is a common procedure in male infants.
- Local anesthesia is frequently used for pain management during circumcision.
- Ensuring safe anesthetic practices in neonates and infants is critical.
Observation:
- Two infant boys experienced severe complications following local anesthesia for ritual circumcision.
- Complications included seizures and respiratory insufficiency, necessitating intubation and anticonvulsive therapy.
- Both infants developed aspiration pneumonia, requiring antibiotic treatment.
Findings:
- The cases highlight the potential risks associated with local anesthesia in very young children.
- Prompt and appropriate medical intervention (intubation, anticonvulsants, antibiotics) led to full recovery.
- No long-term adverse effects (sequelae) were observed in the patients.
Implications:
- Pediatric surgeons and anesthesiologists must exercise caution when calculating local anesthetic doses for infants.
- Healthcare providers should be prepared to manage potential anesthetic complications in this age group.
- This underscores the importance of vigilant monitoring and readiness for emergency interventions in pediatric procedures.
Abstract:
We present two cases in which two boys of four weeks and four and a half months, respectively, experienced seizures and respiratory insufficiency as complications to the local anaesthesia administered for ritual circumcision. They both needed intubation and anticonvulsive therapy and acquired an aspiration pneumonia, which was treated with antibiotics. Both recovered without sequelae. Surgeons should be careful with calculating the maximum safe dose of local anaesthesia for young children and should be prepared to treat complications.
Related Concept Videos
Local Anesthetics: Clinical Application as Spinal Anesthesia
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
General Anesthesia: Overview
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
Stages of General Anesthesia
Parenteral Anesthetics: Overview
Seizures l: Introduction

