Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Classification of Bones01:18

Classification of Bones

13.9K
The bones of the human skeletal system are of varied shapes, sizes, and functions. They can be classified based on their shape and function into four major classes: long bones, short bones, flat bones, and irregular bones. Some classifications include a fifth type, the sesamoid bones, as a separate class, whereas others categorize them under short bones.
Long and Short Bones
The appendicular skeleton, particularly the upper and lower limbs, is primarily made of long and short bones. The...
13.9K
Compact Bone01:27

Compact Bone

21.3K
Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
21.3K
Gross Anatomy of Bone01:17

Gross Anatomy of Bone

14.0K
The two main features of a long bone are the diaphysis and the epiphysis.
The diaphysis is the tubular shaft that runs between the proximal and distal ends of the bone. The walls of the diaphysis are composed of dense and hard compact bone made of numerous osteons — the functional unit of the compact bone. The hollow region in the diaphysis is called the medullary cavity, which harbors the bone marrow. In infants and children, this marrow cavity is filled with red marrow, whereas in...
14.0K
Spongy Bone01:09

Spongy Bone

12.1K
All bones comprise an outer layer of compact bone, and an interior made up of spongy bone tissue, also called cancellous or trabecular bone. In long bones, spongy bone tissue is mainly found in the interior of the epiphyses (broad ends of the bone).
Spongy bone is more porous, and less dense compared to compact bone. It is composed of concentric lamellae that are arranged irregularly to form the trabecular network. In some bones, the spaces between trabeculae contain red marrow, where...
12.1K
Changes in the Appendicular Skeleton with Age01:09

Changes in the Appendicular Skeleton with Age

4.0K
The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
4.0K
Bone Formation by Endochondral Ossification01:24

Bone Formation by Endochondral Ossification

14.5K
Bone formation, or ossification, begins around the sixth to seventh week of embryonic development. Most bones develop from a cartilaginous template through the process of endochondral ossification. Cartilage formation begins when clusters of mesenchymal cells differentiate into chondrocytes. These chondrocytes proliferate rapidly and secrete an extracellular matrix that becomes encased in a membrane called the perichondrium. The resulting cartilage model provides a template that resembles the...
14.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

It's time to look more closely at RYR3.

The Journal of general physiology·2019
Same author

CFTR gets together.

The Journal of general physiology·2019
Same author

Small calcium leaks, big muscle adaptations.

The Journal of general physiology·2019
Same author

Rhomboids make do with a weak hydrogen bond.

The Journal of general physiology·2019
Same author

Investigating an epileptogenic mutation.

The Journal of general physiology·2019
Same author

How a mutation undermines cardiac function.

The Journal of general physiology·2018

Related Experiment Video

Updated: Apr 6, 2026

Non-invasive Skeletal Muscle Quantification in Small Animals Using Micro-computed Tomography
07:33

Non-invasive Skeletal Muscle Quantification in Small Animals Using Micro-computed Tomography

Published on: November 8, 2024

1.0K

Make No Bones about It: Long Bones Scale Isometrically.

Caitlin Sedwick1

  • 1Freelance Science Writer, San Diego, California, United States of America.

Plos Biology
|August 5, 2015
PubMed
Summary
This summary is machine-generated.

This study reveals that long bone growth is isometric, meaning features maintain their relative positions. This process minimizes positional drift during development, ensuring proper skeletal structure.

More Related Videos

Outer-Boundary Assisted Segmentation and Quantification of Trabecular Bones by an Imagej Plugin
09:36

Outer-Boundary Assisted Segmentation and Quantification of Trabecular Bones by an Imagej Plugin

Published on: March 14, 2018

9.9K
Culturing and Measuring Fetal and Newborn Murine Long Bones
06:58

Culturing and Measuring Fetal and Newborn Murine Long Bones

Published on: April 26, 2019

8.8K

Related Experiment Videos

Last Updated: Apr 6, 2026

Non-invasive Skeletal Muscle Quantification in Small Animals Using Micro-computed Tomography
07:33

Non-invasive Skeletal Muscle Quantification in Small Animals Using Micro-computed Tomography

Published on: November 8, 2024

1.0K
Outer-Boundary Assisted Segmentation and Quantification of Trabecular Bones by an Imagej Plugin
09:36

Outer-Boundary Assisted Segmentation and Quantification of Trabecular Bones by an Imagej Plugin

Published on: March 14, 2018

9.9K
Culturing and Measuring Fetal and Newborn Murine Long Bones
06:58

Culturing and Measuring Fetal and Newborn Murine Long Bones

Published on: April 26, 2019

8.8K

Area of Science:

  • Developmental biology
  • Biomechanics
  • Orthopedics

Background:

  • Long bones are complex structures, not simple cylinders.
  • Understanding how their features maintain relative positioning during growth is crucial.

Purpose of the Study:

  • To investigate the growth patterns of long bones.
  • To determine if growth is isometric and how positional accuracy is maintained.

Main Methods:

  • Analysis of long bone growth.
  • Quantitative assessment of feature positioning during development.

Main Results:

  • Long bone growth was found to be isometric.
  • Minimal drift in the relative positioning of bone features was observed.

Conclusions:

  • Isometric growth is key to maintaining the structural integrity of long bones.
  • The skeletal system effectively minimizes positional errors during development.