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Herb-induced cardiotoxicity from accidental aconitine overdose
Sujata Sheth1, Elaine Ching Ching Tan1, Hock Heng Tan2
1Accident and Emergency Department, Changi General Hospital, Singapore.
Singapore Medical Journal
|August 6, 2015
Summary
Accidental aconite overdose can cause fatal heart arrhythmias. This case highlights a patient
Area of Science:
- Toxicology
- Cardiology
- Herbal Medicine Safety
Background:
- Aconite, a traditional Chinese herbal medicine, can cause severe cardiotoxicity and neurotoxicity when overdosed.
- Accidental aconite poisoning poses a significant risk of life-threatening cardiac arrhythmias.
Observation:
- A patient experienced an accidental overdose of aconite from self-prepared Chinese herbal medication.
- The overdose resulted in severe cardiotoxic effects, including ventricular tachycardia, bidirectional ventricular tachycardia, and ventricular fibrillation.
Findings:
- The patient survived the aconite overdose without lasting adverse effects.
- Successful management involved anti-arrhythmic medications, defibrillation, and cardiopulmonary resuscitation.
Implications:
- This case underscores the critical need for caution in preparing and using aconite-containing herbal remedies.
- Prompt and appropriate medical intervention can lead to favorable outcomes in aconite poisoning cases.
- Highlights the importance of understanding potential toxicity of traditional medicines.
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