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Updated: Apr 5, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
(Re)theorizing Integrated Knowledge Translation: A Heuristic for Knowledge-As-Action
Gweneth Hartrick Doane1, Sheryl Reimer-Kirkham, Elisabeth Antifeau
1School of Nursing, University of Victoria, Victoria, British Columbia, Canada (Dr Doane); School of Nursing, Trinity Western University, Langley, British Columbia, Canada (Dr Reimer-Kirkham); Interior Health Authority, Kelowna, British Columbia, Canada (Ms Antifeau); and School of Nursing, University of Victoria, Victoria, British Columbia, Canada (Dr Stajduhar).
Abstract:
Approaches to knowledge translation (KT) have undergone substantial transformation in an effort to find more effective strategies to ensure the best available knowledge informs nursing practice. However, the fundamental epistemology underpinning KT itself has gone largely unquestioned. Of particular concern is the inadequacy of current representational models to depict the complex, social process of KT. To address the limitations of representational models we propose an inquiry heuristic that conceptualizes KT as a knowledge-as-action process. Developed through a series of KT research projects, the heuristic is intended to guide the KT process and support effective navigation in the complexities of contemporary health care milieus.
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