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Updated: Apr 5, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Translational Scholarship and a Palliative Approach: Enlisting the Knowledge-As-Action Framework
Sheryl Reimer-Kirkham1, Gweneth Hartrick Doane, Elisabeth Antifeau
1School of Nursing, Trinity Western University, British Columbia, Canada (Dr Reimer-Kirkham); School of Nursing, University of Victoria, British Columbia, Canada (Drs Doane and Stajduhar); Interior Health Authority, British Columbia, Canada (Ms Antifeau); School of Nursing, University of British Columbia, Canada (Dr Pesut and Ms Porterfield); and Fraser Health Authority, British Columbia, Canada (Mss Roberts and Wikjord).
Abstract:
Based on a retheorized epistemology for knowledge translation (KT) that problematizes the "know-do gap" and conceptualizes the knower, knowledge, and action as inseparable, this paper describes the application of the Knowledge-As-Action Framework. When applied as a heuristic device to support an inquiry process, the framework with the metaphor of a kite facilitates a responsiveness to the complexities that characterize KT. Examples from a KT demonstration project on the integration of a palliative approach at 3 clinical sites illustrate the interrelatedness of 6 dimensions-the local context, processes, people, knowledge, fluctuating realities, and values.
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