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[How to stop hormone replacement therapy?]
Duodecim; Laaketieteellinen Aikakauskirja
|August 7, 2015
Summary
Hormone replacement therapy (HRT) cessation can be immediate or gradual, with equal risks of symptom recurrence. Women can choose their preferred method for stopping HRT, as restarting rates do not differ between techniques.
Area of Science:
- Gynecology
- Endocrinology
- Pharmacology
Context:
- Hormone replacement therapy (HRT) is a common treatment for menopausal and urogenital symptoms.
- Guidelines recommend using the lowest effective dose for the shortest necessary duration.
- Annual review for dose reduction or discontinuation is advised.
Purpose:
- To compare the effectiveness and patient outcomes of immediate versus gradual cessation of hormone replacement therapy.
- To inform clinical practice regarding HRT discontinuation strategies.
Summary:
- Both immediate and gradual cessation of HRT result in similar risks of menopausal symptom recurrence.
- There is no significant difference in the rate of restarting HRT between the two cessation methods.
- Women can independently choose their preferred method of HRT cessation, as immediate cessation is often successful and avoids complex dose-reduction instructions.
Impact:
- Empowers women to make informed decisions about discontinuing HRT based on personal preference and successful outcomes.
- Simplifies the discontinuation process by validating immediate cessation as a viable and effective option.
- Potentially reduces patient burden by eliminating the need for complicated dose-reduction regimens.