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Updated: Apr 5, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

88.5K

[A posseting infant]

Laura Merras-Salmio, Kaija-Leena Kolho

    Duodecim; Laaketieteellinen Aikakauskirja
    |August 7, 2015
    PubMed

    Insights

    Infant reflux is usually physiological and resolves on its own. Treatments like proton pump inhibitors are ineffective, and special formulas are unnecessary for healthy infants experiencing reflux.

    Area of Science:

    • Pediatric Gastroenterology
    • Infant Health and Nutrition

    Context:

    • Increasing referrals for infant regurgitation and suspected reflux disease.
    • Reflux as a common physiological phenomenon in infants, often misdiagnosed as disease.

    Purpose:

    • To evaluate the efficacy of pharmacologic therapies for infant reflux.
    • To clarify the management and prognosis of reflux symptoms in infants.

    Summary:

    • Reflux symptoms in infants typically resolve spontaneously.
    • Proton pump inhibitors show no greater efficacy than placebo for infant reflux.
    • No evidence supports changing from breast milk to specialized formula for reflux management.

    Impact:

    • Highlights the self-limiting nature of infant reflux.
    • Discourages unnecessary medical interventions and formula changes.
    • Emphasizes the excellent prognosis for reflux in healthy infants.

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