Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bioremediation00:46

Bioremediation

23.0K
Bioremediation is the use of prokaryotes, fungi, or plants to remove pollutants from the environment. This process has been used to remove harmful toxins in groundwater as a byproduct of agricultural run-off and also to clean up oil spills.
23.0K
Microbial Bioremediation of Hydrocarbons01:26

Microbial Bioremediation of Hydrocarbons

65
Bioremediation is an environmentally sustainable process that employs living organisms—primarily microorganisms—to degrade or neutralize pollutants from contaminated environments. In oil spills and hydrocarbon pollution, bioremediation involves the use of hydrocarbon-degrading bacteria to transform toxic compounds into less harmful substances. This approach leverages natural microbial metabolic processes and is considered both cost-effective and ecologically favorable compared to...
65
Microbial Bioremediation of Pesticides01:28

Microbial Bioremediation of Pesticides

58
Pesticides often feature structurally complex chemical architectures, incorporating halogen groups and multiple aromatic rings. These characteristics confer high chemical stability, rendering many pesticides resistant to natural degradation processes. This resistance poses significant environmental concerns, as persistent pesticide residues can accumulate in ecosystems and affect non-target organisms.Despite the inherent stability of many pesticides, certain microorganisms possess the metabolic...
58
Biodeterioration01:28

Biodeterioration

64
Biodeterioration refers to the unwanted alteration of materials caused by microorganisms—especially fungi—which damage both organic substrates (paper, wood, textiles) and inorganic ones (stone, plaster, glass). Unlike abiotic decay, biodeterioration results from biological activity that produces physical disruption and chemical degradation.Physical deterioration occurs as fungal hyphae penetrate pores, cracks, and surface irregularities. Hyphal turgor pressure, thigmotropic growth...
64

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Metabolic thermodynamics: pertinent reference state and energy potentials.

The FEBS journal·2026
Same author

In situ characterization of amine-forming enzymes shows altered oligomeric state.

Protein science : a publication of the Protein Society·2024
Same author

Improvement of α-amino Ester Hydrolase Stability via Computational Protein Design.

The protein journal·2023
Same author

EnzymeML: seamless data flow and modeling of enzymatic data.

Nature methods·2023
Same author

Mutations Increasing Cofactor Affinity, Improve Stability and Activity of a Baeyer-Villiger Monooxygenase.

ACS catalysis·2022
Same author

Selectivity and kinetic modeling of penicillin G acylase variants for the synthesis of cephalexin under a broad range of substrate concentrations.

Biotechnology and bioengineering·2022
Same journal

Sustainable Refrigerants, Policy Drivers, and Emerging Technologies.

Annual review of chemical and biomolecular engineering·2026
Same journal

Introduction.

Annual review of chemical and biomolecular engineering·2026
Same journal

A Resonant Life.

Annual review of chemical and biomolecular engineering·2026
Same journal

Jamming and Yielding in Dense Suspensions.

Annual review of chemical and biomolecular engineering·2026
Same journal

Beyond Clean: Unraveling Phase Behavior and Rheology of Soaps.

Annual review of chemical and biomolecular engineering·2026
Same journal

The Nonequilibrium Self-Consistent Generalized Langevin Equation Theory of Glasses and Gels.

Annual review of chemical and biomolecular engineering·2026
See all related articles

Related Experiment Video

Updated: Apr 5, 2026

Immobilization of Multi-biocatalysts in Alginate Beads for Cofactor Regeneration and Improved Reusability
09:27

Immobilization of Multi-biocatalysts in Alginate Beads for Cofactor Regeneration and Improved Reusability

Published on: April 22, 2016

18.3K

Biocatalysis: A Status Report.

Andreas S Bommarius1

  • 1School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, Georgia 30318;

Annual Review of Chemical and Biomolecular Engineering
|August 7, 2015
PubMed
Summary
This summary is machine-generated.

Advances in biocatalysis and enzyme engineering address key limitations. Novel protein engineering tools and rational stabilization models are enhancing the design, stability, and availability of biocatalysts for broader applications.

Keywords:
biocatalystenzymeprotein engineeringstabilization

More Related Videos

Bioprospecting of Extremophilic Microorganisms to Address Environmental Pollution
07:20

Bioprospecting of Extremophilic Microorganisms to Address Environmental Pollution

Published on: December 30, 2021

4.4K
Author Spotlight: Scaling Microalgal Biotechnology for Enhanced Biomethane Production
07:34

Author Spotlight: Scaling Microalgal Biotechnology for Enhanced Biomethane Production

Published on: March 22, 2024

3.6K

Related Experiment Videos

Last Updated: Apr 5, 2026

Immobilization of Multi-biocatalysts in Alginate Beads for Cofactor Regeneration and Improved Reusability
09:27

Immobilization of Multi-biocatalysts in Alginate Beads for Cofactor Regeneration and Improved Reusability

Published on: April 22, 2016

18.3K
Bioprospecting of Extremophilic Microorganisms to Address Environmental Pollution
07:20

Bioprospecting of Extremophilic Microorganisms to Address Environmental Pollution

Published on: December 30, 2021

4.4K
Author Spotlight: Scaling Microalgal Biotechnology for Enhanced Biomethane Production
07:34

Author Spotlight: Scaling Microalgal Biotechnology for Enhanced Biomethane Production

Published on: March 22, 2024

3.6K

Area of Science:

  • Biocatalysis and Enzyme Engineering
  • Protein Engineering
  • Biotechnology

Background:

  • Biocatalysts offer high activity and selectivity but face limitations.
  • Key drawbacks include lack of designability, limited stability, and insufficient availability.
  • These limitations hinder the general applicability of biocatalysis.

Purpose of the Study:

  • To review the current status of biocatalysis and enzyme engineering.
  • To highlight recent advances addressing existing drawbacks.
  • To discuss progress in biocatalyst design, stability, and characterization.

Main Methods:

  • Review of novel experimental and computational protein engineering tools.
  • Application of rational models to quantitatively describe biocatalyst deactivation.
  • Analysis of experimental data on enzyme stabilization through accumulated mutations.

Main Results:

  • Significant progress in protein engineering tools enhances biocatalyst development.
  • Rational models provide quantitative descriptions of biocatalyst deactivation.
  • Experimental evidence supports the concept of cross-stabilization against multiple stresses.

Conclusions:

  • Biocatalyst designability and stability have been substantially improved.
  • The availability of well-characterized biocatalysts is increasing.
  • Advances pave the way for wider adoption of biocatalysis in various applications.