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Laparoscopic Anatomic S7+S8d Resection Preserving Inferior Right Hepatic Vein and S6 with Right Hepatic Vein Transection
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Beyond cure: preventing and managing the complications of end-stage liver disease

Marina Berenguer1, María García-Eliz, Chiara Baiguera

  • 1aLiver Unit, Ciberehd and University of Valencia, Valencia, Spain bDivision of Infectious Diseases AO Ospedale Niguarda Ca' Granda, Milano, Italy.

Current Opinion in HIV and AIDS
|August 7, 2015
PubMed

Insights

Hepatitis C virus (HCV) eradication in cirrhosis patients leads to favorable outcomes, including liver health improvements and extrahepatic benefits. Continued monitoring after sustained virologic response (SVR) is crucial for managing potential complications and liver dysfunction.

Area of Science:

  • Hepatology
  • Virology
  • Gastroenterology

Background:

  • Cirrhosis poses significant health risks.
  • Hepatitis C virus (HCV) infection is a leading cause of cirrhosis.
  • Effective antiviral therapies offer potential for HCV eradication.

Purpose of the Study:

  • To define the implications of HCV eradication in patients with cirrhosis.
  • To assess the impact of sustained virologic response (SVR) on patient outcomes.
  • To identify critical factors in managing patients post-HCV eradication.

Main Methods:

  • Literature review of studies on HCV eradication in cirrhotic patients.
  • Analysis of outcomes associated with sustained virologic response (SVR).
  • Evaluation of extrahepatic benefits and long-term follow-up strategies.

Main Results:

  • SVR is linked to favorable outcomes, including cirrhosis regression.
  • Extrahepatic benefits include improved quality of life and reduced risk of diabetes and cardiovascular diseases.
  • Identifying the 'point of no return' for clinical improvement post-eradication is critical in decompensated cirrhosis.

Conclusions:

  • HCV eradication can lead to cirrhosis regression or stabilization.
  • Post-eradication follow-up is essential for early detection of HCC and liver dysfunction.
  • HCV eradication offers significant extrahepatic advantages beyond liver health.
Abstract

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