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Parasellar syndrome caused by plasma cell leukemia
L D Bellan1, T A Cox, R D Gascoyne
1Department of Ophthalmology, University of British Columbia, Vancouver.
Canadian Journal of Ophthalmology. Journal Canadien D'Ophtalmologie
|December 1, 1989
Summary
This study reports a rare case of plasma cell leukemia initially presenting with third cranial nerve palsy due to a parasellar plasmacytoma. It highlights a unique central nervous system manifestation of this hematologic malignancy.
Area of Science:
- Neurology
- Hematology
- Oncology
Background:
- Plasma cell leukemia is a rare, aggressive hematologic malignancy.
- Intracranial plasmacytomas are uncommon tumors that can arise independently or in association with plasma cell disorders.
Observation:
- A 71-year-old male presented with incomplete third cranial nerve palsy.
- Imaging revealed a parasellar mass, later diagnosed as a plasmacytoma.
Findings:
- The patient was diagnosed with plasma cell leukemia, with the parasellar plasmacytoma as the initial manifestation.
- This represents the first reported case of plasma cell leukemia where a central nervous system sign was the presenting symptom.
Implications:
- This case underscores the importance of considering plasma cell leukemia in the differential diagnosis of central nervous system lesions, even with unusual initial presentations.
- Further understanding of the relationship between plasma cell leukemia and intracranial plasmacytomas is warranted.