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Published on: November 4, 2010
Casting a look at pediatric plastic bronchitis
Tin Jasinovic1, Frederick K Kozak1, J Paul Moxham1
1Division of Pediatric Otolaryngology, British Columbia's Children's Hospital, Vancouver, BC, Canada.
Insights
Plastic bronchitis in children presents with bronchial casts, often requiring rigid bronchoscopy for removal. Recurrent cases and co-morbidities like heart disease may increase mortality risk.
Area of Science:
- Pediatric Pulmonology
- Respiratory Medicine
- Critical Care
Background:
- Plastic bronchitis involves the formation of bronchial casts, posing a significant respiratory challenge in pediatric patients.
- Understanding the clinical spectrum and effective management is crucial for improving outcomes.
Purpose of the Study:
- To review the clinical presentations of pediatric plastic bronchitis.
- To evaluate the management strategies employed for this condition.
- To add to the existing knowledge base, including data from the International Plastic Bronchitis Registry.
Main Methods:
- A retrospective chart review was conducted.
- Data from seven pediatric patients requiring rigid bronchoscopy for bronchial cast removal over 17 years were analyzed.
Main Results:
- Seven pediatric patients underwent rigid bronchoscopy for bronchial cast removal.
- The mean age at presentation was 60 months, with a mean follow-up of 53 months.
- Co-morbidities included congenital heart disease, chronic pulmonary disorders, and sickle cell disease. Four patients experienced recurrent casts, and two required bronchoscopy while on extracorporeal membrane oxygenation (ECMO) with special precautions.
Conclusions:
- Bronchial casts in children can manifest acutely or sub-acutely.
- Recurrent casts are uncommon but can be fatal in conjunction with severe cardiac disease.
- Adjunctive topical therapies require further investigation, and safeguarding ECMO catheters is essential during procedures.
Objectives:
To review clinical presentations and management strategies for children with plastic bronchitis.
Methods:
Retrospective chart review.
Results:
Seven patients required rigid bronchoscopy to remove bronchial casts over a 17-year study period. Mean age at presentation was 60 months. Mean follow-up was 53 months. Co-morbidities included: congenital heart disease (n=3), chronic pulmonary disorders (n=2) and sickle cell disease (n=1). 4 patients required multiple bronchoscopies for recurrent casts. Adjunctive topical therapies were administered in all 7 patients, without complication. Rigid bronchoscopy for cast removal was performed in 2 patients who were on extra-corporal membrane oxygenation (ECMO), using special precautions to safeguard the ECMO catheters.
Conclusions:
Bronchial casts in children may present acutely or sub-acutely. Recurrent casts are unusual; however, in combination with severe cardiac disease may lead to mortality. Adjunctive topical therapies are still under investigation. Special safeguards for ECMO catheters are imperative. This case series complements and adds to the International Plastic Bronchitis Registry.
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