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Transthoracic Echocardiography to Assess Post-Resuscitation Left Ventricular Dysfunction After Acute Myocardial Infarction and Cardiac Arrest in Pigs

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Hyperdynamic left ventricular ejection fraction in the intensive care unit.

Joseph R Paonessa^1,2,3, Thomas Brennan⁴, Marco Pimentel⁵

¹Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA, 02215, USA. jrpaonessa@gmail.com.

Critical Care (London, England)

|August 8, 2015

Summary

This summary is machine-generated.

Hyperdynamic left ventricular ejection fraction (HDLVEF) in the ICU is linked to higher mortality. This finding may serve as a prognostic marker for critically ill patients.

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Area of Science:

Cardiology
Critical Care Medicine
Echocardiography

Background:

Limited data exists on hyperdynamic left ventricular ejection fraction (HDLVEF) in intensive care units (ICUs).
Understanding HDLVEF's prevalence and impact is crucial for critical care patient management.

Purpose of the Study:

To compare characteristics and outcomes of ICU patients with HDLVEF versus normal ejection fraction.
To identify factors associated with HDLVEF and its prognostic significance.

Main Methods:

Retrospective cohort study using the MIMIC-II database.
Included 2867 adult ICU patients; 324 had HDLVEF (ejection fraction >70%).
Excluded patients with ejection fraction <55%.

Main Results:

HDLVEF associated with female sex, older age, hypertension, and cancer.
Patients with HDLVEF showed increased 28-day mortality (OR 1.38, p=0.02) in adjusted analysis.
Multivariate analysis controlled for age, sex, comorbidities, and interventions.

Conclusions:

HDLVEF indicates increased 28-day mortality in ICU patients.
HDLVEF may serve as a prognostic gravity marker.
Further research needed on HDLVEF patient response to interventions and pharmacologic modulation.