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Related Experiment Video

Updated: Apr 5, 2026

Utilization of Ultrasound Guided Tissue-directed Cellular Implantation for the Establishment of Biologically Relevant Metastatic Tumor Xenografts

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Extrarenal nephroblastoma.

Wojciech Apoznański¹, Krystyna Sawicz-Birkowska¹, Mateusz Palczewski¹

¹Department of Pediatric Surgery and Urology, Medical University, Wrocław, Poland.

Central European Journal of Urology

|August 8, 2015

Summary

Extrarenal nephroblastoma, a rare childhood cancer, presents without typical symptoms or imaging findings. Diagnosis relies on histology after tumor resection, with treatment mirroring that of intrarenal Wilms tumor.

Keywords:

extrarenal location nephroblastoma

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A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies

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Published on: April 12, 2017

Area of Science:

Pediatric Oncology
Surgical Pathology

Background:

Nephroblastoma (Wilms tumor) is a common pediatric solid tumor.
Extrarenal nephroblastoma is an exceptionally rare variant, requiring histological confirmation and an extrarenal location.

Purpose of the Study:

To review current data on extrarenal nephroblastoma.
To highlight diagnostic challenges and management strategies.

Main Methods:

Selective literature review of extrarenal nephroblastoma cases.
Analysis of reported clinical presentations, diagnostic imaging, and histological findings.

Main Results:

Extrarenal nephroblastoma lacks characteristic clinical manifestations; symptoms vary by location and stage.
Imaging modalities (US, CT, MRI) can detect tumors but lack specific radiological features.
Typical locations differ by sex: retroperitoneum in males, inguinal region in females.

Conclusions:

Diagnosis of extrarenal nephroblastoma is primarily histological, confirmed post-resection.
Management protocols for extrarenal nephroblastoma are comparable to those for intrarenal Wilms tumor.