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Updated: Sep 29, 2026

Live Imaging of Dense-core Vesicles in Primary Cultured Hippocampal Neurons
Published on: May 29, 2009
Toward live-cell imaging of dopamine neurotransmission with fluorescent neurotransmitter analogues
Hui-Jen Lin1, Hsueh-Han Lu, Kuan-Miao Liu
1Department of Applied Chemistry and Institute of Molecular Science, National Chiao Tung University, Hsinchu 30010, Taiwan. ianliau@mail.nctu.edu.tw ykl@cc.nctu.edu.tw.
Abstract:
We report a novel 'fluorescent dopamine' that possesses essential features of natural dopamine. Our method is simple and is readily extended to monoamine neurotransmitters such as L-norepinephrine, serotonin and GABA, providing a more practical approach. Because of its compatibility with sensitive fluorescent measurements, we envisage that our approach will have a broad range of applications in neural research.

