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Nerves Regulate Cardiomyocyte Proliferation and Heart Regeneration

Ahmed I Mahmoud1, Caitlin C O'Meara1, Matthew Gemberling2

  • 1Department of Stem Cell and Regenerative Biology, Harvard University, and the Brigham Regenerative Medicine Center, Brigham and Women's Hospital and Harvard Medical School, Cambridge, MA 02139, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA; Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

Developmental Cell
|August 11, 2015
PubMed
Summary

Nerves are essential for heart regeneration in zebrafish and mice. Inhibiting nerve function reduces cardiomyocyte proliferation and impairs regeneration, highlighting nerves

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