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Updated: Jul 15, 2026

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Tissue tension permits β-catenin phosphorylation to drive mesoderm specification in human embryonic stem cells

Nadia M E Ayad1, Aisha Almsoud2, Johnathon N Lakins3

  • 1Graduate Program in Bioengineering, University of California, San Francisco and University of California, Berkeley, San Francisco, CA 94143, USA; Center for Bioengineering and Tissue Regeneration, Department of Surgery, University of California, San Francisco, San Francisco, CA 94143, USA.

Developmental Cell
|July 13, 2026
PubMed

Keywords:
Wntcytoskeletal tensiongastrulationgastruloidshuman embryonic stem cellsmechanical forcesmechanotransductionmesodermtraction force microscopyβ-catenin

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