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Relationship between the fatty acid composition and the type of antibiotics produced by Streptomyces lasaliensis
M Podojil1, N Steinerová, J Cudlín
1Department of Biogenesis of Natural Substances, Czechoslovak Academy of Sciences, Prague.
Journal of Basic Microbiology
|January 1, 1989
Abstract:
The GC-MS method was used to analyze fatty acids in a parent strain of Streptomyces lasaliensis and its two mutants producing only lasalocid or quinomycin. The biosynthesis of these substances bears relation to differences in the relative proportion of fatty acids. Biosynthetic relationships were revealed between the starter fatty acid units, their precursors, i.e. valine, leucine and isoleucine, and the type of the antibiotic produced.