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A Laser-induced Mouse Model of Chronic Ocular Hypertension to Characterize Visual Defects
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[Masked hypertension]

Guillaume Bobrie

    Bulletin De L'Academie Nationale De Medecine
    |August 12, 2015
    PubMed

    Insights

    Masked hypertension, high blood pressure detected outside clinic visits, is common in treated patients. It carries a poor cardiovascular prognosis, similar to sustained hypertension, despite normal in-office readings.

    Area of Science:

    • Cardiology
    • Hypertension Research
    • Clinical Medicine

    Context:

    • Masked hypertension is defined as normal blood pressure (BP) in a clinical setting but elevated BP during ambulatory or home monitoring.
    • This condition is prevalent, especially among individuals undergoing antihypertensive therapy.
    • It frequently coexists with other cardiovascular risk factors.

    Purpose:

    • To highlight the clinical significance and prognostic implications of masked hypertension.
    • To underscore the diagnostic challenge and potential underestimation of cardiovascular risk associated with this condition.

    Summary:

    • Masked hypertension presents a diagnostic dilemma, with normal readings in medical settings masking underlying high blood pressure.
    • Patients with masked hypertension exhibit a poorer cardiovascular prognosis, comparable to those with sustained hypertension.
    • The underlying pathophysiology remains unclear, and evidence from controlled treatment trials is lacking.

    Impact:

    • Recognizing masked hypertension is crucial for accurate cardiovascular risk assessment.
    • This condition may necessitate tailored management strategies beyond standard in-office BP monitoring.
    • Further research into its mechanisms and effective treatments is warranted to improve patient outcomes.

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