Related Experiment Video
Updated: Apr 5, 2026
07:36
Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
Published on: November 20, 2015
12.0K
Prenatal evaluation of atelencephaly
Usha D Nagaraj1,2, Anne Lawrence3, L Gilbert Vezina4,5
1Department of Radiology and Medical Imaging, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave., Cincinnati, OH, 45229, USA. usha.nagaraj@cchmc.org.
Pediatric Radiology
|August 12, 2015
Summary
Atelencephaly, a severe brain malformation, was identified in a fetus using ultrasound and MRI. This case details unique fetal MRI findings for this rare condition.
Area of Science:
- Medical Imaging
- Developmental Biology
- Fetal Medicine
Background:
- Atelencephaly is a rare, lethal congenital brain malformation.
- It involves the underdevelopment of the prosencephalon (forebrain).
- Facial anomalies, like cyclopia, can be associated with atelencephaly.
Observation:
- This report details a case of fetal atelencephaly.
- Characteristic ultrasound findings were observed.
- Fetal magnetic resonance imaging (MRI) was performed.
Findings:
- The study presents novel fetal MRI findings in a case of atelencephaly.
- These MRI findings have not been previously documented in medical literature.
- The combination of ultrasound and MRI provided a comprehensive assessment.
Implications:
- This case expands the understanding of atelencephaly imaging.
- It highlights the utility of fetal MRI in diagnosing rare brain malformations.
- Improved diagnostic capabilities can aid in genetic counseling and management.
Related Concept Videos
01:07Teratogenicity
4.5K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
4.5K
01:30Neurulation
47.4K
Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the...
47.4K
01:21Aneurysm II: Clinical Manifestations and Diagnostic Studies
532
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
532