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Related Concept Videos

Tissue Transplantation01:24

Tissue Transplantation

1.2K
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
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Bone Marrow Sampling and Transplants01:22

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Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
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Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

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Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
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Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

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A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
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Updated: Apr 5, 2026

Murine Skin Transplantation
06:42

Murine Skin Transplantation

Published on: January 16, 2008

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Retransplantation.

Clemens Aigner1

  • 1Department of Thoracic Surgery, Medical University of Vienna, Vienna, Austria.

Current Opinion in Organ Transplantation
|August 12, 2015
PubMed
Summary
This summary is machine-generated.

Pulmonary retransplantation outcomes improve with careful patient selection. Ambulatory patients with obstructive chronic lung allograft dysfunction benefit most, while awake bridging offers equal outcomes for deteriorating patients.

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Area of Science:

  • Cardiology
  • Pulmonary Medicine
  • Transplantation Surgery

Background:

  • Rising lung transplant numbers increase demand for retransplantation due to lung allograft dysfunction.
  • Donor organ scarcity necessitates identifying recipients who most benefit from retransplantation.

Purpose of the Study:

  • To review current strategies for patient selection in pulmonary retransplantation.
  • To highlight advancements in bridging techniques and their impact on outcomes.

Main Methods:

  • Review of recent literature on pulmonary retransplantation outcomes.
  • Analysis of patient selection criteria and bridging strategies.
  • Evaluation of outcomes based on patient status (elective vs. acute) and allograft dysfunction type.

Main Results:

  • Elective retransplantation in ambulatory patients with chronic lung allograft dysfunction yields the best outcomes.
  • Survival after elective retransplantation has improved due to refined patient selection.
  • Advances in bridging devices, including awake bridging, improve outcomes for acutely deteriorating patients.

Conclusions:

  • Optimal patient selection is critical for successful pulmonary retransplantation.
  • Ambulatory patients with obstructive chronic lung allograft dysfunction are ideal candidates.
  • Awake bridging strategies can achieve outcomes comparable to elective procedures for selected patients.