Related Experiment Video
Updated: Apr 5, 2026

Author Spotlight: Exploring Salidroside's Molecular Mechanisms in Breast Cancer Treatment
Published on: June 9, 2023
Thymoquinone Anticancer Discovery: Possible Mechanisms
1Fac. Of Vet. Med., Damanhour Univ., Egypt., 27 Qratum Square, Behind Damanhour Stadium, Damanhour, Egypt. ali.elfar@damanhour.edu.eg.
Abstract:
Medicinal plants are known for their many advantages, including the ability to treat diseases such as cancer. Nigella sativa and its active constituent thymoquinone (TQ) have long been used in traditional medicine for treating various conditions related to the respiratory and gastrointestinal systems as well as breast, colorectal, gastric, hepatic, pancreatic cancers and leukemia. TQ has been documented to possess chemo-preventive and chemotherapeutic antitumor effects. Studies reported that TQ inhibits the growth of cancer cells in animal models and culture tumors. This review summarizes the in vitro and in vivo possible mechanisms of TQ anticancer effect.
Related Concept Videos
Electron Transport Chain: Complex I and II
ROS generation is regulated and maintained at moderate levels necessary...
Pharmacogenetics of Drug Targets: β₂-Adrenergic Receptors, Apo E, Thymidylate Synthase
Drugs that Destabilize Microtubules
Inhibition of Cdk Activity
Cancer-Critical Genes II: Tumor Suppressor Genes
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
Cancer-Critical Genes II: Tumor Suppressor Genes
