Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Monoamines, glucose metabolism, and impulse control.

M Linnoila, J DeJong, M Virkkunen

Psychopharmacology Bulletin

|January 1, 1989

Summary

Biochemical markers in cerebrospinal fluid significantly predicted future criminal behavior and suicide attempts in violent offenders. This study highlights the link between neurochemistry and recidivism in forensic populations.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

"Sucking the trouble" out of troubleshooting wound vacs: Video based curriculum development and implementation in a live tissue model.

American journal of surgery·2025

Same author

Psychological outcomes of evening and night closed-loop insulin delivery under free living conditions in people with Type 1 diabetes: a 2-month randomized crossover trial.

Diabetic medicine : a journal of the British Diabetic Association·2016

Same author

TFIIAalpha/beta-like factor is encoded by a germ cell-specific gene whose expression is up-regulated with other general transcription factors during spermatogenesis in the mouse.

Biology of reproduction·2001

Same author

The role and limitations of the Cairo International Conference on Population and Development.

Social science & medicine (1982)·2000

Same author

Functional interactions between an atypical NF-kappaB site from the rat CYP2B1 promoter and the transcriptional repressor RBP-Jkappa/CBF1.

Nucleic acids research·2000

Same author

Microsomal GST-I: genomic organization, expression, and alternative splicing of the human gene.

Biochimica et biophysica acta·1999

Area of Science:

Neuroscience
Forensic Psychology
Biochemistry

Background:

Early studies in the 1980s examined cerebrospinal fluid monoamine metabolites and glucose metabolism in violent offenders.
Previous research explored links between biological factors and criminal behavior.

Purpose of the Study:

To investigate the predictive value of biochemical variables for recidivism and suicide attempts in a cohort of violent offenders.
To differentiate individuals with and without recidivism and suicide attempts using behavioral, diagnostic, and biochemical data.

Main Methods:

Follow-up study of 58 violent offenders and impulsive fire setters originally assessed in the early 1980s.
Analysis of cerebrospinal fluid monoamine metabolite concentrations and glucose metabolism.
Assessment of behavioral, diagnostic, and biochemical variables for discrimination.

Main Results:

Biochemical variables demonstrated significant discriminatory power between groups with and without recidivism and suicide attempts.
Specific monoamine metabolite concentrations and glucose metabolism patterns were associated with adverse outcomes.

Conclusions:

Cerebrospinal fluid biochemical markers are significant predictors of recidivism and suicide attempts in violent offenders.
Neurochemical profiles may aid in identifying individuals at higher risk for future criminal behavior and self-harm.

Related Experiment Videos