Related Experiment Video
Updated: Nov 24, 2025

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
Published on: April 12, 2021
Medication adherence among patients with chronic conditions in Italy
Francesco Napolitano1, Paola Napolitano1, Italo Francesco Angelillo2
1Department of Experimental Medicine, Second University of Naples, Via Luciano Armanni, 5, 80138 Naples, Italy.
Background:
The aims of the cross-sectional study were to measure the extent of adherence to prescribed medications among patients affected by chronic diseases and to identify the predictors of the adherence.
Methods:
The study was conducted between March and December 2014 among 633 outpatients in four hospitals in Italy. Data were collected using a face to face interview at the time of their visit to the hospital. The Morisky Medication Adherence 4-item Scale was used to measure patients' self-reported adherence.
Results:
The majority of the patients were male (51.7%), the mean age was 63.2 years, one-third had at least a high school diploma or equivalent, 34.6% was employed, and the main diseases were hypertension, diabetes, and chronic obstructive pulmonary disease. A total of 39.3% patients reported themselves as being adherent to medications over the 4 weeks preceding their medical specialist's visit. Patients were more likely to adhere to medications if they had a college degree or higher level of education, a higher score of the Katz index, took a lower number of total pills per day, and did not use pill organizers. Patients who have never forgotten to take medications over the 4 weeks preceding their medical specialist's visit were 46.1%.
Conclusions:
The findings emphasize the need for improving information for the individuals affected by chronic diseases concerning the risks of non-adherence in order to encourage responsible behaviour to prescribed medications.

