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Updated: Apr 5, 2026

Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice
Published on: July 31, 2019
Asymmetry of interhemispheric communication.
1Department of Neurological and Visual Sciences, Physiology Section, University of Verona, 8 Strada Le Grazie, 37134, Verona, Italy.
The corpus callosum (CC) facilitates interhemispheric communication, with faster transmission from the right to the left hemisphere. This right-to-left asymmetry may stem from neuronal projections and aid rapid left-hemisphere response.
Area of Science:
- Neuroscience
- Cognitive Neuroscience
Background:
- The corpus callosum (CC) is crucial for interhemispheric communication.
- Previous research indicates asymmetric callosal transmission, faster from right to left.
Purpose of the Study:
- Investigate the functional meaning and neural basis of callosal transmission asymmetry.
- Explore the hypothesis that greater right-to-left neuronal projections underlie this asymmetry.
Main Methods:
- Behavioral experiments
- Electrophysiological experiments
Main Results:
- Callosal transmission is consistently faster from the right to the left hemisphere.
- This asymmetry is observed across various behavioral and cognitive processes.
Conclusions:
- The right-to-left asymmetry in callosal transmission is a significant finding.
- Potential explanations include a larger number of neurons projecting from the right to the left hemisphere.
- This asymmetry might facilitate rapid left-hemisphere access for responses in tasks dominated by the right hemisphere.
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