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Fibromuscular dysplasia in donor kidneys--experience with three cases
Insights
Kidney grafts with medial fibroplasia can develop stenosis. Balloon catheter dilatation successfully treated progressive renal artery stenosis in a transplant recipient.
Area of Science:
- Nephrology
- Vascular Surgery
- Transplantation Medicine
Background:
- Medial fibroplasia is a vascular condition that can affect kidney grafts.
- Pre-existing vascular affection in donor kidneys poses a risk for recipients.
Observation:
- Three patients received kidney grafts with known medial fibroplasia.
- Two grafts were from cadaveric donors; one was from a living related donor.
Findings:
- Only one recipient developed renal graft artery stenosis and hypertension.
- Successful treatment of progressive stenosis was achieved using balloon catheter dilatation.
Implications:
- Balloon angioplasty is an effective treatment for post-transplant renal artery stenosis.
- Careful donor selection and monitoring may be crucial for kidney transplantation outcomes.
Abstract:
In 1987, three patients received kidney grafts bearing medial fibroplasia at our hospital. Two of the grafts were from a cadaveric donor and one was from a living related donor kidney. The vascular affection was known before transplantation. Only one of the recipients developed stenosis and hypertension. With balloon catheter dilatation, the progressive stenosis of the renal graft artery could, however, be successfully corrected.