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Immunoadjuvant Therapy and Noninvasive Ventilation for Acute Respiratory Failure in Lung Tuberculosis: A Case Study
René Agustín Flores-Franco1, Dahyr Alberto Olivas-Medina1, Cesar Francisco Pacheco-Tena2
1Departamento de Medicina Interna, Christus Muguerza Hospital Del Parque, Calle Dr. Pedro Leal Rodriguez 1802, Colonia Centro, 31000 Chihuahua, CHIH, Mexico.
Abstract:
Acute respiratory failure caused by pulmonary tuberculosis is a rare event but with a high mortality even while receiving mechanical ventilatory support. We report the case of a young man with severe pulmonary tuberculosis refractory to conventional therapy who successfully overcame the critical period of his condition using noninvasive ventilation and immunoadjuvant therapy that included three doses of etanercept 25 mg subcutaneously. We conclude that the use of etanercept along with antituberculosis treatment appears to be safe and effective in patients with pulmonary tuberculosis presenting with acute respiratory failure.
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