Related Experiment Video
Updated: Apr 5, 2026

Gastrointestinal Motility Monitor GIMM
Published on: December 1, 2010
Segmental colonic length and mobility
M Phillips1, A Patel1, P Meredith1
1Department of Physiology, Development and Neuroscience, University of Cambridge, UK.
Rectosigmoid length significantly influences total colon length. Ascending and descending colon segments are more mobile than traditionally taught, impacting colorectal procedures and potentially colonoscopy difficulty in females. Jackson's membrane is common.
Area of Science:
- Anatomy
- Surgical Anatomy
Background:
- Colonic length and mobility vary regionally, impacting surgical and endoscopic procedures.
- Accurate anatomical understanding is crucial for effective colorectal interventions.
Purpose of the Study:
- To refine anatomical knowledge of the human colon by detailing segmental lengths and mobility.
- To investigate the relationship between colonic segments and overall colonic length variability.
Main Methods:
- Examination of 35 cadavers to measure lengths of the caecum, ascending, transverse, descending, and rectosigmoid colon.
- Characterization of colonic mobility based on mesenteric attachments.
- Documentation of Jackson's membrane presence.
Main Results:
- Mean total colonic length was 131.2cm (SD: 13.4cm).
- Rectosigmoid length was the best predictor of total colonic length.
- Significant mobility observed in the ascending (66%) and descending (33%) colon, more common in females.
- Jackson's membrane present in 66% of subjects.
Conclusions:
- Rectosigmoid length variability is a primary driver of total colonic length variation.
- Ascending and descending colon segments exhibit greater mobility than traditionally assumed, necessitating a revision of anatomical teaching.
- Ascending colon mobility in females may explain challenges during colonoscopy.
- Jackson's membrane is a frequent anatomical finding.
Related Concept Videos
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
Large Intestine
The ileocecal sphincter, a mucous membrane fold, guards the opening from the ileum to the large intestine. This valve permits material from the small intestine to pass into the large intestine. Attached to the ileocecal valve is the cecum. This small pouch, approximately 6 cm long, has a twisted, coiled tube known as...
Drugs Affecting GI Tract Motility: Serotonin Receptor Agonists
Gastrointestinal Motility Disorders
Endoscopic Procedures II: Colonoscopy
Histology of the Large Intestine
The innermost mucosa layer comprises simple columnar epithelium, lamina propria, and muscularis mucosae. This layer is primarily populated with absorptive cells, tasked with water absorption, and goblet cells, responsible for secreting mucus to...

