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Updated: Apr 5, 2026

A Syngeneic Orthotopic Osteosarcoma Sprague Dawley Rat Model with Amputation to Control Metastasis Rate
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Sclerosing rhabdomyosarcoma presenting on the knee-joint
Yuanyin Zheng1, Xiaobin Liu, Yingyu Mao
1Department of Pathology, Mindong Hospital of Fujian Medical University, Fudong Hospit Ningde, Fujian, China.
Abstract:
Sclerosing rhabdomyosarcoma is a rare pathological diagnosis that easily misdiagnosed. The majority of cases reported the tumor increased rapidly in size and the Ki-67 proliferation index ranged from 10% to 60%. Here, we report the first case of the tumor increased very slowly for 20 years and the Ki-67 proliferation index was lower than 2%, and discuss its histological features and immunohistochemical reactivity with Desmin and Ki-67 and so on.
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