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Renal donors with prostate cancer, no longer a reason to decline
S Dholakia1, R Johns1, L Muirhead1
1Imperial College Healthcare NHS Trust, West London Renal and Transplant Centre, London, United Kingdom.
Objective:
To fully assess the true risk of prostate cancer transmission in during renal transplantation.
Methods:
A full review of all existing literature relevant to the topic.
Results:
There has not been a single documented case of transmission of prostate cancer during renal transplant. Prostate cancer in deceased organ donors has an incidence estimated between 3% and 18.5% and over 100 transplants have been performed using organs from donor with proven prostate cancer without issue.
Conclusion:
Transmission of prostate cancer through kidney transplantation seems very unlikely. The risks of remaining on the waiting list are outweighed by a transmission risk and the potential benefit makes the case to have clear guidelines about donor prostate malignancy when accepting potential organs.
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