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Imaging and Analysis of Single Optically Trapped Gold Nanoparticles Using Spatial Modulation Spectroscopy.

Mary Sajini Devadas1, Zhongming Li1, Gregory V Hartland1

  • 1Department of Chemistry and Biochemistry, University of Notre Dame, 251 Nieuwland Science Hall, Notre Dame, Indiana 46556-5670, United States.

The Journal of Physical Chemistry Letters
|August 18, 2015
PubMed
Summary

Researchers measured single nanoparticles in solution using spatial modulation spectroscopy. This new method analyzes optical properties of optically trapped nanoparticles without surface interference.

Keywords:
optical trappingsingle nanoparticle spectroscopyspatial modulation spectroscopy

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Area of Science:

  • Nanotechnology
  • Optical Spectroscopy
  • Physical Chemistry

Background:

  • Spatial modulation spectroscopy (SMS) measures extinction cross sections and spectra of single nanoparticles.
  • SMS provides detailed information on particle size, shape, and environment.
  • Traditionally, SMS requires particles immobilized on a substrate.

Purpose of the Study:

  • To demonstrate the application of SMS to single, optically trapped nanoparticles in solution for the first time.
  • To overcome the limitations of surface-bound particle analysis.

Main Methods:

  • Optically trapping single gold nanoparticles (as small as 15 nm) in a liquid environment.
  • Utilizing a galvo-scanning mirror system to modulate the probe laser beam position.
  • Scanning the modulated laser beam over the trapped particle to record extinction spectra.

Main Results:

  • Successfully trapped and interrogated single gold nanoparticles in solution using SMS.
  • Demonstrated the feasibility of analyzing nanoparticles free from substrate influence.
  • Obtained extinction cross sections and spectra of individual nanoparticles in liquid.

Conclusions:

  • Spatial modulation spectroscopy can be effectively applied to optically trapped nanoparticles in solution.
  • This technique enables precise measurement of optical properties in liquid environments.
  • Opens new avenues for studying nanoparticle behavior and interactions in biologically relevant media.