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Future Perspectives of Radionanomedicine Using the Novel Micelle-Encapsulation Method for Surface Modification
Yun-Sang Lee1, Yong-Il Kim1, Dong Soo Lee2
1Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea ; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Republic of Korea.
Abstract:
The emerging radionanomedicine has multifunctional and theranostic purposes. For these purposes, radionanomedicine should achieve the efficient and specific delivery of therapeutic agents by multifunctional characteristics, using low amounts of nanomaterials in vivo. Recent research on radiolabeled micelle-encapsulated nanomaterials has been made on the their efficacy and safety using a one-step surface modification method (Jeong's method). This one-step multifunctional approach to the nanoparticle can be the important challenge in producing effective nanoplatforms for cancer imaging and therapy.
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