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Related Experiment Video

Updated: Apr 5, 2026

Processing of Primary Brain Tumor Tissue for Stem Cell Assays and Flow Sorting
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Banking Brain Tumor Specimens Using a University Core Facility.

Amade Bregy1, Kyriakos Papadimitriou1, David A Faber1

  • 11 Department of Neurological Surgery, University of Miami Miller School of Medicine , Miami, Florida.

Biopreservation and Biobanking
|August 18, 2015
PubMed
Summary

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Brain tumor banking is crucial for research. The University of Miami/Sylvester Tissue Bank Core Facility (UM-TBCF) has collected 225 central nervous system tumor specimens since 2011, with glioblastoma and meningioma being the most common types.

Area of Science:

  • Neuro-oncology
  • Cancer Research
  • Biobanking

Background:

  • Human cancer tissue banking has become increasingly vital for advancing cancer research over the last three decades.
  • High-quality central nervous system (CNS) tumor tissue samples are essential for comprehensive research.
  • Establishing and maintaining a reliable tissue bank requires strict adherence to ethical guidelines and robust record-keeping.

Purpose of the Study:

  • To document the experience of collecting brain tumor specimens at the University of Miami/Sylvester Tissue Bank Core Facility (UM-TBCF).
  • To ensure a consistent supply of high-quality CNS tumor tissue for research purposes.
  • To highlight the importance of ethical considerations and standardized procedures in tissue collection.

Main Methods:

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  • Collaboration with the University of Miami/Sylvester Tissue Bank Core Facility (UM-TBCF).
  • Informed consent obtained from patients, adhering to Institutional Review Board (IRB) and Health Insurance Portability and Accountability Act (HIPAA) regulations.
  • Collection and cataloging of 225 brain tumor specimens since 2011.
  • Main Results:

    • A total of 225 brain tumor specimens have been successfully banked for research.
    • The most frequent tumor histology identified was glioblastoma (22.1%), followed by meningioma (18.1%).
    • Patient demographics reflect Florida's population: 45.1% White non-Hispanic, 23% Hispanic/Latino, and 14% Black/African American.

    Conclusions:

    • The UM-TBCF successfully established a valuable repository of CNS tumor specimens.
    • Glioblastoma and meningioma are the predominant tumor types within the banked collection.
    • The tissue bank serves a diverse patient population, offering unique samples for cancer research.