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Updated: Apr 5, 2026
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Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma
Published on: September 15, 2023
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[Surgical treatment for primary papillary thyroid cancer: a Meta-analysis]
Summary
Partial thyroidectomy (PT) offers lower risks of recurrent laryngeal nerve and parathyroid injury compared to total thyroidectomy (TT) for papillary thyroid cancer. PT is a suitable option for early-stage disease, ensuring comparable survival rates.
Area of Science:
- Endocrine Surgery
- Oncology
- Surgical Outcomes Research
Background:
- Papillary thyroid cancer treatment involves surgical options like total thyroidectomy (TT) and partial thyroidectomy (PT).
- Choosing between TT and PT requires evaluating risks of injury, complications, recurrence, and survival rates.
Purpose of the Study:
- To compare total thyroidectomy (TT) and partial thyroidectomy (PT) for papillary thyroid cancer.
- To assess and contrast associated injuries, postoperative complications, recurrence rates, and survival outcomes.
- To provide a basis for selecting the optimal surgical procedure for papillary thyroid cancer.
Main Methods:
- A comprehensive literature search was conducted using databases like CNKI, Wang Fan, PubMed, Central, and CBM.
- Included studies compared total thyroidectomy (TT) and partial thyroidectomy (PT) for papillary thyroid cancer.
- Data retrieval extended up to December 31, 2013, with strict exclusion criteria applied to 4630 initially identified literatures, leaving 20 retrospective studies for analysis.
Main Results:
- Partial thyroidectomy (PT) demonstrated significantly lower rates of recurrent laryngeal nerve injury (2.0% vs. 5.9% for TT) and parathyroid injury (0.8% vs. 4.9% for TT).
- Survival rates at 10 years were comparable between TT (95.24%-100%) and PT (96.8%-99.2%).
- Unstaged recurrence rates were higher for PT (12.6%) compared to TT (4.7%). However, for Stage I, recurrence was 7.8% for PT vs. 4.9% for TT, and for Stage II, PT had a significantly higher recurrence rate (15.9%) than TT (0.5%).
Conclusions:
- Both total thyroidectomy (TT) and partial thyroidectomy (PT) achieve good survival rates for primary papillary thyroid carcinoma.
- Partial thyroidectomy (PT) is associated with lower rates of recurrent laryngeal nerve and parathyroid injury.
- Partial thyroidectomy (PT) is a favorable surgical choice for early-stage papillary thyroid carcinoma, balancing oncologic control with reduced morbidity.
