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Updated: Apr 5, 2026

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Probiotic Studies in Neonatal Mice Using Gavage
Published on: January 27, 2019
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[PROBIOTICS, NUTRITIONAL STATUS AND RESISTANCE TO RESPIRATORY INFECTIONS IN INFANTS].
Summary
Probiotic use of Enterococcus faecium L3 in infants reduced acute respiratory infections (ARI) and improved body mass index (BMI) in the first month. This probiotic intervention also supported vaccination schedules in infants.
Area of Science:
- Pediatrics
- Microbiology
- Immunology
Context:
- Infants in institutional care are susceptible to infections.
- Acute Respiratory Infections (ARI) are a common health concern in infants.
- Nutritional status is crucial for infant development and immunity.
Purpose:
- To evaluate the efficacy of a liquid probiotic Enterococcus faecium L3 in preventing ARI in infants.
- To assess the impact of this probiotic on infant nutritional status.
- To determine the probiotic's effect on infant vaccination tolerance.
Summary:
- A randomized controlled trial involved 29 infants, with 14 receiving daily Enterococcus faecium L3 probiotic and 15 in the control group.
- The probiotic group showed a significant reduction in ARI cases (p < 0.05) and a higher increase in Body Mass Index (BMI) during the first month.
- Probiotic use was associated with improved tolerance for routine vaccinations, with 18.1% more infants receiving multiple vaccinations simultaneously.
Impact:
- Probiotic supplementation with Enterococcus faecium L3 may enhance infant immunity against respiratory infections.
- Early probiotic intervention can positively influence infant growth and nutritional parameters.
- This probiotic may facilitate the timely completion of infant vaccination schedules.
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