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gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair
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Population-Wide Screening for Germline BRCA1 and BRCA2 Mutations: Too Much of a Good Thing?

Matthew B Yurgelun1, Elaine Hiller2, Judy E Garber3

  • 1Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA matthew_yurgelun@dfci.harvard.edu.

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
|August 19, 2015
PubMed
Abstract

No abstract available in PubMed .

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Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...
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